Matthew C Weber

Matthew Charles Weber, 66, of Sheffield Lake and Philadelphia, PA, died peacefully, surrounded by his family members, on Friday November 25, 2022 at University Hospital St. John Medical Center in Westlake. He died unexpectedly, a mere six days after being diagnosed with pancreatic cancer. Matt was preceded in death by his parents, Leona and Nelson Weber, his brother Frank Weber, and his sister Patricia Luchkowsky. He is survived by his wife, Julie M. McDonald, and his brother Michael Weber and sister-in-law Patt Weber. He is also survived by his much loved nieces and nephews: Gabriel Luchkowsky (Alicia Hines); Lara (David) Marsh; Annie (Michael) Zimmerman; Kiva (C.J.) Kisabeth; Kay Weber; Michael (Kristen) Weber; and Max (Kristi) Weber, as well as by nine grandnephews and one grandniece. Matt was also cherished by his many McDonald family in-laws, nieces, and nephews. Born in Lorain, OH, Matt found such great happiness when he moved back to this area in June 2021. Would that he might have had more time here to spend with his family and friends, but so grateful that he had these precious eighteen months. He enjoyed living along Life Erie, buying a boat with his brother, and watching the two bald eagles that regularly perch in our tall elm tree overlooking the water. And as a devoted Buckeye fan, he was thrilled to attend a game in the “horseshoe” in Columbus Ohio this fall. (Thank you C.J. and Kiva!) A proud graduate of Lorain Catholic High School and The Ohio State University, Matt completed a Ph.D. in immunology at Case Western University, studying under his mentor and friend of some thirty-five years, Dr. Mark Tykocinski. After a post-doc at Case Western, he followed Mark to the University of Pennsylvania and then to Thomas Jefferson University, both in Philadelphia – which is where he met his wife. His recent research was focused on pioneering immunotherapeutic strategies that invoked engineered proteins and cells. Along with his colleagues, he designed several novel classes of fusion proteins, which have therapeutic potential for cancer. A memorial mass is planned for Thursday, December 29, 2022 at 11:00 a.m. at Nativity BVM Catholic Church, 1454 Lexington Ave, in Lorain. Interment will be private. In addition, a memorial service will be held this spring in the Chapel at Saint Joseph’s University in Philadelphia. In lieu of flowers, please consider a donation to Nativity BVM Catholic Church

Matthew C Weber

February 10, 1956 - November 25, 2022